National Institutes of Health Clinical Center


Ethics of Clinical Research

Ethical Issues in Research with Special Populations

Regulations call for additional protections for populations for whom the standard protections may not be sufficient. For example, U.S. federal regulations include specific additional requirements for research with children, prisoners, and pregnant women, and call for additional safeguards to protect vulnerable adults. A good deal of recent work has focused on the ethical concerns raised by, and possible safeguards to address, research with individuals who lack access to health care. The Department's work in this area focuses on evaluating to what extent the existing and proposed protections are sufficient, what additional requirements are needed for the identified individuals and groups, and what other individuals and groups might need additional protections.

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